5htp ~ where can i find this?

[tommy-boi]

where can I find this stuff? does it need prescription?

I want to take some of this because many people says it helps the E depression you get the following day

has anyone taken this before? what's the best time to take it? how many do I need if I am poping 2 pills?

thanks

[James]

at any health store

[NeVeRLooKBacK]

just take it before you leave the party
get some vitamin C


you can preload but you should do that for a few days before hand
just take it as your leaving the party or you come down

[MC Hammered]

If you can find the Jarrow brand buy that as it's the best quality 5htp I have found.

Preload a few days before you decide to drop and then right after to reduce the "moody" aftereffects of low serotonin levels.

Do not take 5htp the day you plan to drop as it'll mash out the high instead of intensifying it.

If you want more information do a search in the drugs forum as I posted a bit on this topic in the past.

[impure]

Kripps.

[D-Vine]

You can buy it at superstore. It's in the vitamins and supplements section.
I take it through my high, but that's just me.
And like already mentioned, Vitamin C. Take before, during, and after.

[MissBehavior]

Try and get the 100mg caplets. I know Kripp's sells them. They're kinda pricey, but where your brain is concerned, I think it's money well spent.

[BenGiovanni]

Originally Posted by MC Hammered

If you can find the Jarrow brand buy that as it's the best quality 5htp I have found.

Preload a few days before you decide to drop and then right after to reduce the "moody" aftereffects of low serotonin levels.

Do not take 5htp the day you plan to drop as it'll mash out the high instead of intensifying it.

If you want more information do a search in the drugs forum as I posted a bit on this topic in the past.

ive dropped 5htp before last years Insomnia, then popped 2 hours later...i was DONEEEEEE!!!!! lol
Dave remembers me when I was flying
but the high got bad towards the end.

[sinnerman]

Originally Posted by MissBehavior

Try and get the 100mg caplets. I know Kripp's sells them. They're kinda pricey, but where your brain is concerned, I think it's money well spent.

5HTP might make you feel better, but it won't do much to prevent brain damage. Brain damage results from dopamine following the expenditure of serotonin. Antioxidants greatly reduce this damge (eg. Beta-carotene, Vitamin C, and especially vitamin E). Careful though, too much b-c or vitC are pro-oxidants; never pop without vitamin E!

[MC Hammered]

^^^ I think you missed out a whole bunch with that cut and paste there.

Brian damage is suspected when the dopamine that is in the brain is oxidized along with the serotonin.

When you oxidize dopamine it turns into a compound that is similar to bleach.

Antioxidants help reduce the oxidation that happens and therefore reduces the amount of "bleaching" that may occur after you drop.

[sinnerman]

^^^
Actually, no. I'm pre-med at UBC and that's a little from the research for my paper in an anatomy and physiology course. It's biochemistry, it's impossible not to miss a whole bunch, even if you're writing a book on it. But...I can explain with a little more detail for you:



After taking MDMA, your serotoninergic synapses are flooded with serotonin. This serotonin is eventually broken down and inefficiently recycled. The amount of serotonin in the pre-synaptic neuron has been temporarily, but significantly, reduced. 5HTP (along with normal diet) will slowly replenish these stores reversing the depression that follows MDMA use.

Dopamine concentrations are normally low in serotoninergic synapses. But, about 6 hours after taking MDMA, the dopamine to serotonin ratio in the synapse is very high. Consequently, some dopamine is taken up by the serotonin re-uptake centers and uses transport proteins designed for serotonin to pass back into the pre-synaptic axon. Dopamine causes a small amount of damage (comparable to light drinking) to serotoninergic neurons. The enzyme monoamine oxidase (present in these neurons) breaks down dopamine into quinones (the bleach-like chemicals), but also other metabolites. Homovanillic acid (one of these metabolites) is the main cause for concern, although quinones and other metabolites are also damaging. These chemicals wreak havoc on the axon of the neuron. This is where significant long-term damage occurs. Eventually, the neuron's ability to transport serotonin in the brain is greatly reduced, even if the neurons remain responsive to it. As a result, increasing the amount of or sensitivity to serotonin does not reverse ecstasy damage. The pathways by which serotonin achieve its affects have been destroyed/damaged.

Dopamine will still damage your brain while taking MDMA & antioxidants. However--and I think this is what you should have been trying to say--the benefit occurs because antioxidants promptly take up the oxidized metabolites of dopamine, binding with them to form other, non-volatile compounds that can be safely filtered from the body without causing significant damage to the neuron. :mrt:

[liquidblue]

You can get 5-htp off of ebay for hella cheap. Oh and from what iv heard/experianced taking 5-htp a few hours b4 u roll makes your high more mellow and less speedy. Personally i dont liek the speedy effects at all, I like chill blissfulness.

Im not sure how much good taking 5-htp a few days b4 rollign will do...?

[zarlon]

ahhh old thread revival... noooo!!!!

[Vitamin-X]

Before I Rave, I take alpha olipic acid. It's an antioxidant that is both water and fat soluable. Therefore it does the work of both Vitamin C and E.
I also take 1000mg of Magnesium oxide to help with jaw clenching.

As far as post loading:
Take 100mg of 5-htp "after" your roll. The idea is to make sure the E has cycled out of your system. I'm told a 5-htp caused roll is no fun at all.
then take 300mg the following day.
If you want they have coated types (more expensive) that don't upset your stomach (if you're sensitive to that).

[FeelGood]

The shit we do so we can have some candy at raves.

[MC Hammered]

Originally Posted by liquidblue

You can get 5-htp off of ebay for hella cheap. Oh and from what iv heard/experianced taking 5-htp a few hours b4 u roll makes your high more mellow and less speedy. Personally i dont liek the speedy effects at all, I like chill blissfulness.

Im not sure how much good taking 5-htp a few days b4 rollign will do...?

If you are gong to dig in the archives why don't you continue and you'll find all the answers you need.

BTW... speedy E = large % of crystal meth... 5-htp does nothing to reduce this effect.

[Felix]

I read that if you take an MAOI (monoamine oxidase inhibitor - ie: Saint John's Wort, Prozac) about 6 hours after you pop that it will help reduce the brain damage
The reason behind this is because these prevent the neurons from taking the "bleach like stuff" back into your seratonin center (yah not the right terms, it's been waaay to long since I read-up on this stuff) and that way there is less damage to the axon as mentioned in sinnerman's post
But the only way for it to be effective is to take it during the time that the stuff is getting taken back up, so if you pop multiple times in the night or forget to take the MAOI on time then it doesn't really help. Also if you take the MAOI while you are still high then it can cause damage since it is preventing the good stuff from getting taken back up and it will over-load the recievers on the other end (again, sorry 'bout the terminology, but hopefully you get the point)
But if you're the type to pop in line so yer high by the time you get to the stage and know how to tell time when yer scetchy then it's worth getting some saint john's wort (also available at health food store) to keep a few more of those precious brain cells that we love to hurt so much
If anyone dissagrees then say so, it has been a while since I grad'ed and I don't really read this stuff for recreational reading.

[MC Hammered]

The suspected brain damage occurs when your body starts oxidizing the dopamine that also floats around in your brain.

When you oxidize dopamine it has a similar chemical structure to bleach.

Taking a MAOI 6 hours after your trip isn't going to do anything because the oxidation is happening already.

Taking it before you pop is like going on a roller coaster without brakes.

[-evil-duerr-]

Originally Posted by Felix

I read that if you take an MAOI (monoamine oxidase inhibitor - ie: Saint John's Wort, Prozac) about 6 hours after you pop that it will help reduce the brain damage
The reason behind this is because these prevent the neurons from taking the "bleach like stuff" back into your seratonin center (yah not the right terms, it's been waaay to long since I read-up on this stuff) and that way there is less damage to the axon as mentioned in sinnerman's post
But the only way for it to be effective is to take it during the time that the stuff is getting taken back up, so if you pop multiple times in the night or forget to take the MAOI on time then it doesn't really help. Also if you take the MAOI while you are still high then it can cause damage since it is preventing the good stuff from getting taken back up and it will over-load the recievers on the other end (again, sorry 'bout the terminology, but hopefully you get the point)
But if you're the type to pop in line so yer high by the time you get to the stage and know how to tell time when yer scetchy then it's worth getting some saint john's wort (also available at health food store) to keep a few more of those precious brain cells that we love to hurt so much
If anyone dissagrees then say so, it has been a while since I grad'ed and I don't really read this stuff for recreational reading.

dont tell people to pop prozac after e. thats fuckin stupid. prozac is an ssri. ssri's are sick and horrible for people's health

[Felix]

oops, my bad
that's what I read a while back, guess I was missinformed, sorry