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| The Chronical Chill out, spark a jay, and enter the chronical. |
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Dec 05, 03
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Extacy and Antidepressants
Last night my friend took Extasy at a school dance and she was on antidepressants too..but she told me that she wasnt taking htem anymore in the summer..But she could also be lieing. I was just wondering what that will do to u if u mix those too? Cause i was told that it can kill u cause those 2 drugs dont go good together. Im very concerned about her. Cause i dont want to lose a friend. And she wont listen to what i say. So i need help on what to tell her.
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Dec 05, 03
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it can cause death or brain damage ill try and find a site that explains how mdma works and contrasts what antidepresseants do and how they can cause problems together. My best friend takes anti's too but when he plans on doin E he stops the antis for a week before use just to make sure.
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Dec 05, 03
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ya...cause she told me that shes been off them for awhile...but who knows if shes lieing..I just think its dumb to do E if ur on antidepressants...cause in the morning..i feel like shit..and just image how someone that needs Antidepressants would feel..they r already depressed..u know..i think its pretty dumb
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Dec 05, 03
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Boyer’s primary criticism of Erowid was in reference to a comment made about the potential use of SSRIs to reduce negative side effects of MDMA. They commented that “The combined use of SSRIs (selective serotonin reuptake inhibitors) or MAOIs (monoamine oxidase inhibitors) with drugs possessing serotonergic activity such as MDMA has led to serotonin syndrome in selected patients.”
While it is true that combining MAOIs with MDMA increases risks of serotonin syndrome, there is little evidence to suggest the same is true about SSRIs. The serotonin syndrome occurs following the use of serotomimetic agents (serotonin reuptake inhibitors, tricyclic and tetracyclic antidepressants, tryptophan, 3,4-methylenedioxy-methamphetamine, dextromethorphan, meperidine, S-adenosylmethionine) alone or in combination with monoamine oxidase inhibitors. It is characterized by various combinations of myoclonus, rigidity, hyperreflexia, shivering, confusion, agitation, restlessness, coma, autonomic instability, low-grade fever, nausea, diarrhea, diaphoresis, flushing, and rarely, rhabdomyolysis and death.
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Dec 05, 03
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Some big words..lol..but ya..thats fucked up..but i think it would be different for a gurl. Cause u know how some gurls r on e..they always get sick. Guys can handle it better. Well thats what i think..
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Dec 05, 03
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You take a risk everytime you pop a cap that the filler isn't Draino or rat poisening, if you're lucky the worst thing you get is Jib or Baking soda.
Anti-depressants stabalize the chemical balance of the brain, reducing the extreme up's and down's. When you take a cap of e the mdma causes a seratonin dump through your body, something wich cannot be re-created on a whim or even a couple of days. By taking a cap of e when on anti-depressants you're pretty much throwing your body back into a manic state of uber ups and downs. The fact people go around and pop random caps of e and hence random mix's of drugs without passing a second thought, all the while worrying over whether mixing anti-depressants is shere stupidity. Do you know the long term effects of mdma, jib, ketamine, or any other 'rave' drugs, and the harm it causes your body? I didn't think so. Maybe look into that and start worrying about what's going into your body in the first place, one at a time, before worrying about mixing. By being informed of what's going into you and the effects and side affects of what that causes doesn't eliminate the risk, nothing is ever 100% safe, but it greatly reduces it while providing the knowledge of what to do should something go wrong. not that i know anything about drugs though...cuz i know shit all about shit, really. Rave. Last edited by Goat; Dec 05, 03 at 06:40 AM.
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Dec 05, 03
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In simple terms taking MDMA with antidepressants is like driving a speeding car without brakes.
You'll go for a ride and you have no way of knowing when it will stop.
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Dec 05, 03
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this post is saying that there's little evidence out there to say that SSRI's will contribute to this serotonin syndrome, however, is she does happen to be on some MAOI, it'll increase the chances. whether or not the source is reliable is another question though.... but commonsensically speaking, I'd have to agree with Goat. I mean, after a huge dump of serotonin, the excess serotonin in the presynaptic cleft is probably washed away faster than it can be taken back up, which I can only imagine will eventually exert a negative feedback loop, leading to a lesser release of serotonin. mix that in with some anti-depressants and I can only imagine would result in an emotional roller coaster! --Joanne :P Last edited by Joanne; Dec 05, 03 at 06:46 AM.
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Dec 05, 03
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Just be careful, i wouldn't recommend it. I know people who have, they've been fine. I'm on them, i was fine. Didn't feel any differnt. I stopped taking them for about a week before hand to make sure.
I did GHB once, way too fast, it made me sick, i was vommiting, i had to go the doc's, i never felt so sick in my life. Ever since then i've been really careful, plus I don't snort anything but Coke now. GHB is STUPID!
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Dec 05, 03
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hahahahahaha That only usually happens if you liquid too hard.
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Dec 05, 03
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actually i dont know what the fuck im tlakin about..i cant remember shit from bio psych, that was two years ago and i poped alot of caps inbetween then and now. e blows...i think i need some antidepressants because i did too much of it and now im emotionally fucked Last edited by SEAN!; Dec 05, 03 at 07:42 AM.
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Dec 05, 03
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Dec 05, 03
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I dont know anythiong about mixing the two, but she's obviously on antidepressants for a reason and doing e while you are, or well EVER have had emotional prblems like that is not a good idea.
I'm sure you know or someone has mentioned already taht E fucks with your seritonin level, if you are allready depressed it just magnifies it all. Trust me I know, I used to be very depressed and after doing E I would sometimes stay in bed and cry for about a week. Tell your friend to stay the fuck away from E not because the mixture of the two drugs may be potentially dangerous, but because a depressed person using E is much more dangerous than it is in the first place.
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Dec 05, 03
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Alot of the times depression has more to do with the way you think or the things going on in your life and how you handle them, but regardless of the reason... fucking up the chemical that regulates your mood just makes the situation worse. Also, finding something that seems to make all your pain and unhappiness go away even if only temporary, can lead to addiction. Winston described it perfectly, if you get ahold of something so powerful and comforting when you are having a hard time otherwise, then you might never know when to stop. That or you either don't want to, or can't stop.
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Dec 05, 03
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and just to clarify, there have been tons of research done on identical twins with depression and scientists have only found a 50% concordance rate. what does this most likely mean? that genetics only account for HALF of what actually cause depression! environment and how people perceive situations also play a role. --Joanne :P
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Dec 05, 03
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Dec 05, 03
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If you are taking anti depressants, and decide to take e, its a waste of money cause you wont feel the full effect of the E. if she still wants to take it, tell her to stop taking antis for at least a couple of weeks cause thats how long it could take to fully leave your system. DOnt worry she aint gonna die or anything as some people said on this topic. check www.bluelight.com if you want more info lots of drug info on this site. :smoke1:
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Dec 06, 03
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^ what a brillianbt idea. Lets stop taking antidepressants to do drugs. woohoo.
I'm not all for pumping people full of pills just because they feel depressed, but she just might need them and telling her to get off them to do ecstacy is FUCKING STUPID. There are potentially serious side effects that can spring from her stopping her antidepresants, especially without doing it properly and not on doctors orders. And did I mention, doing e isn't the smartest thing in the first place. Going off of prescription drugs to get the "full effect" is well.. I allready mentioned how ridiculous and idiotic that is, so I'm hoping you get the point.
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Dec 06, 03
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you're completely right. if the drug that she is on is an SSRI she won't feel any of the effects of the mdma. she will still feel the effects of any adulterants in the pill though. again, as mentioned before, if she is on an MAOI, then she very well might die. though, as she's still alive, she's probably on an SSRI. might be good to check, still. Quote:
you're completely wrong. antidepressants usually require long periods of time before they begin to work. if you skip a few weeks in the meantime, all the time that you have been on them will have been lost, and you'd have to start over at baseline again. another thing is that withdrawal from SSRIs IS NOT FUCKING PLEASANT. i went off celexa over a period of a month and a half, slowly lowering my dosage. i felt like shit the entire time. suggesting going cold turkey is sure to make this poor become a basketcase. Quote:
erowid.org is good. and the dancesafe website used to have a good tutorial about what ecstasy does to the brain and what they suspect SSRIs do to it.
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Dec 08, 03
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Miss spank, chill out, i could bitch at them about it or give some of my ideas. yeesh. Ink, bluelight isnt my only source but its an interesting site, and have more drug info then fnk. i like it cause you can get some info( real or not ) on how people feel on certain drugs or whatever. and for the two weeks of being off it, that was just a guess so of course it could be longer :smoke1: peace
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Dec 08, 03
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